Filamin A anticorps (AA 1725-1775)

N° du produit ABIN7454720

Cet anticorps anti-Filamin A est un anticorps Lapin Polyclonal détectant Filamin A dans WB, IP et IHC (fp). Adapté pour Humain et Souris.

Aperçu rapide pour Filamin A anticorps (AA 1725-1775) (ABIN7454720)

Antigène: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Filamin A est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-Filamin A anticorps

Épitope: AA 1725-1775

Fonction: Rabbit anti-Filamin A Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1725 and 1775

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Filamin A

Antigène: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Autre désignation: Filamin A

Sujet: Background: Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able to act as a link between cell membrane receptors and intracellular signaling proteins. Defects in filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development.

ID gène: 2316

NCBI Accession: NP_001447

UniProt: P21333

Pathways: TCR Signaling, Maintenance of Protein Location